“...I think it would be nice if Hermione and Ron ended up together, because they… "
nice reason Emma, becasue they what?... she couldn't find any good or quick reason for Ron and Hermione to be together, I think is all about promoting what the WB is doing. She didn't sound that convince at all.

“And that’s the book and the film, not real life!”

"not real life!" so Emma doesn't want Rupert in real life.
She is telling us that while she thinks that R/Hr will end up together, she is telling us that Emma and Rupert is a big NO NO.
Clever girl "not real life!"